Subthreshold depression in patients with Parkinson's disease and dementia––clinical and demographic correlates
Identifieur interne : 000F48 ( Main/Exploration ); précédent : 000F47; suivant : 000F49Subthreshold depression in patients with Parkinson's disease and dementia––clinical and demographic correlates
Auteurs : Uwe Ehrt [Norvège] ; Kolbj Rn Br Nnick [Norvège] ; Peter Paul De Deyn [Belgique] ; Murat Emre [Turquie] ; Sibel Tekin [États-Unis] ; Roger Lane [États-Unis] ; Dag Aarsland [Norvège]Source :
- International Journal of Geriatric Psychiatry [ 0885-6230 ] ; 2007-10.
English descriptors
Abstract
Background: About 40% of the patients with Parkinson's disease (PD) have depressive symptoms, either major depression (MD) or subthreshold depression. Depression was found to be associated with age and age at onset of PD, female gender, more severe parkinsonism, in particular with left‐sided and akinetic‐rigid symptoms, more functional impairment and cognitive impairment. However, the findings are inconsistent and partly contradictory and most of the studies focused on major depression in PD without dementia. The aim of this study was to examine the relationship between subthreshold depression and other clinical features in 538 PD patients with dementia but without MD drawn from a randomized, placebo‐controlled multicentre trial of rivastigmine in PD. Results: One hundred and sixteen patients (21%) had subthreshold depression. Depression was associated with a younger age and age at onset and female gender, but not with severity of parkinsonism, cognition or activities of daily living or laterality of motor symptoms. However, in male patients, an association between depression and left‐sided parkinsonism was found. Conclusion: In contrast to previous findings in PD patients with major depression but without dementia, we found no relationship between subthreshold depression and other clinical symptoms in patients with PDD. Copyright © 2007 John Wiley & Sons, Ltd.
Url:
DOI: 10.1002/gps.1774
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Subthreshold depression in patients with Parkinson's disease and dementia––clinical and demographic correlates</title><author><name sortKey="Ehrt, Uwe" sort="Ehrt, Uwe" uniqKey="Ehrt U" first="Uwe" last="Ehrt">Uwe Ehrt</name></author><author><name sortKey="Br Nnick, Kolbj Rn" sort="Br Nnick, Kolbj Rn" uniqKey="Br Nnick K" first="Kolbj Rn" last="Br Nnick">Kolbj Rn Br Nnick</name></author><author><name sortKey="De Deyn, Peter Paul" sort="De Deyn, Peter Paul" uniqKey="De Deyn P" first="Peter Paul" last="De Deyn">Peter Paul De Deyn</name></author><author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name></author><author><name sortKey="Tekin, Sibel" sort="Tekin, Sibel" uniqKey="Tekin S" first="Sibel" last="Tekin">Sibel Tekin</name></author><author><name sortKey="Lane, Roger" sort="Lane, Roger" uniqKey="Lane R" first="Roger" last="Lane">Roger Lane</name></author><author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:45E7245938BDB5B2F43CB99B3BA82367E42A25EB</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1002/gps.1774</idno><idno type="url">https://api.istex.fr/document/45E7245938BDB5B2F43CB99B3BA82367E42A25EB/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">001764</idno><idno type="wicri:Area/Main/Curation">001522</idno><idno type="wicri:Area/Main/Exploration">000F48</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Subthreshold depression in patients with Parkinson's disease and dementia––clinical and demographic correlates</title><author><name sortKey="Ehrt, Uwe" sort="Ehrt, Uwe" uniqKey="Ehrt U" first="Uwe" last="Ehrt">Uwe Ehrt</name><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Norwegian Centre for Movement Disorders, Stavanger University Hospital</wicri:regionArea><wicri:noRegion>Stavanger University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Br Nnick, Kolbj Rn" sort="Br Nnick, Kolbj Rn" uniqKey="Br Nnick K" first="Kolbj Rn" last="Br Nnick">Kolbj Rn Br Nnick</name><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Norwegian Centre for Movement Disorders, Stavanger University Hospital</wicri:regionArea><wicri:noRegion>Stavanger University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="De Deyn, Peter Paul" sort="De Deyn, Peter Paul" uniqKey="De Deyn P" first="Peter Paul" last="De Deyn">Peter Paul De Deyn</name><affiliation wicri:level="4"><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Neurology, Middelheim Hospital, Laboratory of Neurochemistry and Behaviour, Born‐Bunge Foundation, University of Antwerp</wicri:regionArea><placeName><settlement type="city">Anvers</settlement><region type="district" nuts="2">Province d'Anvers</region></placeName><orgName type="university">Université d'Anvers</orgName></affiliation></author><author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Istanbul Faculty of Medicine, Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Capa Istanbul</wicri:regionArea><wicri:noRegion>Capa Istanbul</wicri:noRegion></affiliation></author><author><name sortKey="Tekin, Sibel" sort="Tekin, Sibel" uniqKey="Tekin S" first="Sibel" last="Tekin">Sibel Tekin</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Novartis Pharmaceuticals Corporation Clinical Research and Development East Hanover, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Lane, Roger" sort="Lane, Roger" uniqKey="Lane R" first="Roger" last="Lane">Roger Lane</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Novartis Pharmaceuticals Corporation Clinical Research and Development East Hanover, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Norwegian Centre for Movement Disorders, Stavanger University Hospital</wicri:regionArea><wicri:noRegion>Stavanger University Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Clinical Medicine, University of Bergen</wicri:regionArea><wicri:noRegion>University of Bergen</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">International Journal of Geriatric Psychiatry</title><title level="j" type="sub">A journal of the psychiatry of late life and allied sciences</title><title level="j" type="abbrev">Int. J. Geriat. Psychiatry</title><idno type="ISSN">0885-6230</idno><idno type="eISSN">1099-1166</idno><imprint><publisher>John Wiley & Sons, Ltd.</publisher><pubPlace>Chichester, UK</pubPlace><date type="published" when="2007-10">2007-10</date><biblScope unit="volume">22</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="980">980</biblScope><biblScope unit="page" to="985">985</biblScope></imprint><idno type="ISSN">0885-6230</idno></series><idno type="istex">45E7245938BDB5B2F43CB99B3BA82367E42A25EB</idno><idno type="DOI">10.1002/gps.1774</idno><idno type="ArticleID">GPS1774</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-6230</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>dementia</term><term>depression</term><term>minor depression</term><term>subthreshold depression</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: About 40% of the patients with Parkinson's disease (PD) have depressive symptoms, either major depression (MD) or subthreshold depression. Depression was found to be associated with age and age at onset of PD, female gender, more severe parkinsonism, in particular with left‐sided and akinetic‐rigid symptoms, more functional impairment and cognitive impairment. However, the findings are inconsistent and partly contradictory and most of the studies focused on major depression in PD without dementia. The aim of this study was to examine the relationship between subthreshold depression and other clinical features in 538 PD patients with dementia but without MD drawn from a randomized, placebo‐controlled multicentre trial of rivastigmine in PD. Results: One hundred and sixteen patients (21%) had subthreshold depression. Depression was associated with a younger age and age at onset and female gender, but not with severity of parkinsonism, cognition or activities of daily living or laterality of motor symptoms. However, in male patients, an association between depression and left‐sided parkinsonism was found. Conclusion: In contrast to previous findings in PD patients with major depression but without dementia, we found no relationship between subthreshold depression and other clinical symptoms in patients with PDD. Copyright © 2007 John Wiley & Sons, Ltd.</div></front></TEI><affiliations><list><country><li>Belgique</li><li>Norvège</li><li>Turquie</li><li>États-Unis</li></country><region><li>New Jersey</li><li>Province d'Anvers</li></region><settlement><li>Anvers</li></settlement><orgName><li>Université d'Anvers</li></orgName></list><tree><country name="Norvège"><noRegion><name sortKey="Ehrt, Uwe" sort="Ehrt, Uwe" uniqKey="Ehrt U" first="Uwe" last="Ehrt">Uwe Ehrt</name></noRegion><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><name sortKey="Br Nnick, Kolbj Rn" sort="Br Nnick, Kolbj Rn" uniqKey="Br Nnick K" first="Kolbj Rn" last="Br Nnick">Kolbj Rn Br Nnick</name></country><country name="Belgique"><region name="Province d'Anvers"><name sortKey="De Deyn, Peter Paul" sort="De Deyn, Peter Paul" uniqKey="De Deyn P" first="Peter Paul" last="De Deyn">Peter Paul De Deyn</name></region></country><country name="Turquie"><noRegion><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name></noRegion></country><country name="États-Unis"><region name="New Jersey"><name sortKey="Tekin, Sibel" sort="Tekin, Sibel" uniqKey="Tekin S" first="Sibel" last="Tekin">Sibel Tekin</name></region><name sortKey="Lane, Roger" sort="Lane, Roger" uniqKey="Lane R" first="Roger" last="Lane">Roger Lane</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F48 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000F48 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:45E7245938BDB5B2F43CB99B3BA82367E42A25EB
|texte= Subthreshold depression in patients with Parkinson's disease and dementia––clinical and demographic correlates
}}
| This area was generated with Dilib version V0.6.23. |  |